Before I start, the things you read here will contradict most of what you read in
articles about IGF-1 and Long R3 IGF-1. More research needs to be done, but
this is the most current and scientifically based information I could find. Maybe
this will help take some of the confusion out of these fairly new peptides.
1.) MYTH: There is a big difference between rhIGF-1 and the most commonly
available form Long R3 IGF-1, and because of this difference in half life of
the peptide, they should be used differently as to when they are injected
and also the dosage.
TRUTH: Technically for bodybuilding pruposes there is no difference
between rhIGF-1 and Long R3 IGF-1. They both have the same local
effect. rhIGF-1 gets neutralized quickly, whereas Long R3 IGF-1 gets to
float around until it finds a receptor.
2.) FACT: IGF-1 is very useful for ONE reason: Used correctly it produces
more muscle cells that we can mature and make grow with weight
training and AAS. If you are using it for anything else you are misusing
it. More muscle cells is clearly the best use for IGF-1. IGF-1 makes
more muscle cells, and it's the only thing that can give it to us. More
cells means more growth, which is our goal.
3.) MYTH: rhIGF-1 is the only form that can be injected in to the muscle to
promote localized growth. Long R3 IGF-1 should be injected into the
bloodsteamin large dosages, between 60 - 100mcg, twice daily.
TRUTH: Long R3 IGF-1 for best results should be injected directly in to
the muscle worked immediately post workout and in smaller dosages,
40 mcg in all bodyparts and 50mcg in quads, divided into each side. For
example, on Bicep day , you would inject 20mcg directly in to each
bicep within 5 minutes post workout. The reason is to cause the IFG-1
to attach to the receptors in the muscle itself. If it is injected in to the
bloodstream in large amounts during the day, it can attach to any IGF
receptors which are located througout the interior membranes of the
body, especially the intestines, the result is you will grow your
intestines. Your intestinal cells will begin to divide and multiply and in a
few months to a year you will have a "perma-gut", and it will keep
growing. Heavy lifting strongly upregulates the IGF-1 receptors on the
stressed muscle, so the muscles you trained are at their beststate for
receiving IGF-1 and growing many new cells. This means PIN
IMMEDIATELY POST WORKOUT and you will get your new muscle cells.
PIN A LESSER AMOUNT and you will only get new muscle cells from your
IGF-1. PIN MORE AND YOU WILL GROW OTHER THINGS SUCH AS A
COLEMAN PERMA-GUT!
FACTS: 40MCG IS plenty! You must realize that this is a huge amount
compared to what the body naturally produces. So 20mcg in each side &
25mcg in the quads: 40-50mcg total, immediately postworkout, in the
muscle worked will let you get plenty of hyperplasia (new cells) without
growing your intestines or other internal organs. Now you won't see major
and immediate mass increases, because that is not what IGF-1 is for.
That's what AAS are for. The newly added muscle cells will take months
to grow, but they will and such a protocol makes using IFG-1 a reasonably
inexpensive protocol. IMPORTANT!!- Research shows that EOD and even
E3rdD IGF-1 treatment is better than ED because ED downregulates the
receptors too quickly. It takes some time for receptors to be able to come
back in full after a megadose of even 20mcg if IGF-1. So you may want to
think about lifting heavy EOD and IFG-1 immediately postworkout every
workout, or 2on/1off and pin the lagging muscle E3D.
FACTS: IGF-1 is synergistic with GH. Most of the effects of GH are
mediated through IGF-1, but not all of them. Among the good effects of
GH that IGF-1 does not exert is anabolism to ligaments. This is just an
example to show that there is benefit to using GH and IGF-1 at the same
time. There is evidence that ED dosing of LR3 reduces GH release in the
body, so it makes plenty of sense to use both at the same time.
SOME CONCLUSIONS:
1.) Immediate Postworkout dosing is all important to creating new cells,
preferably 5 minutes postworkout. One researcher's experience: My
protocol was 5 minutes postworkout in my biceps, delts, and chest
because my research had indicated the postworkout window is very
limited and those were my lagging body parts.
2.) Gains from IGF-1 are difficult to account for. On IGF-1 the gians are
some fat loss, some muscle gain/retention, and many new cells that
will mature and grow in the coming months with lifting and AAS.
3.) Standard Cycle: 40mcg EOD for 4-5 weeks and 4-5 weeks off, and
then repeat the cycle, money permitting. This allow for upgrading of
the receptors. Repeat: EOD or E3D is the optimum protocol.
4.) Injecting posworkout: IGF-1 diluted in AA (Acetic Acid -.5-.6%) is
stable for a year at 98 degrees F, so will keep just fine inside of your
locker at the gym. I wrap my preloaded syringe with an alcohol swab
in a small towel and inject myself in a toilet stall. REMEMBER, IGF-1,
for now, is totally legal, so even if police were brought in they would
only have to apologize politely for the trouble of questioning you,
(in USA)'
I got most of this information from another site, it was much longer, so I
condensed it for you so you could read the highlights. Is all of this true and
accurate? Don't know, but this guy made more sense to me than any other
material I have read. Hope this helps all of you by answering some of your
questions about IGF-1 and Long R3 IGF-1. Fitnessrx
articles about IGF-1 and Long R3 IGF-1. More research needs to be done, but
this is the most current and scientifically based information I could find. Maybe
this will help take some of the confusion out of these fairly new peptides.
1.) MYTH: There is a big difference between rhIGF-1 and the most commonly
available form Long R3 IGF-1, and because of this difference in half life of
the peptide, they should be used differently as to when they are injected
and also the dosage.
TRUTH: Technically for bodybuilding pruposes there is no difference
between rhIGF-1 and Long R3 IGF-1. They both have the same local
effect. rhIGF-1 gets neutralized quickly, whereas Long R3 IGF-1 gets to
float around until it finds a receptor.
2.) FACT: IGF-1 is very useful for ONE reason: Used correctly it produces
more muscle cells that we can mature and make grow with weight
training and AAS. If you are using it for anything else you are misusing
it. More muscle cells is clearly the best use for IGF-1. IGF-1 makes
more muscle cells, and it's the only thing that can give it to us. More
cells means more growth, which is our goal.
3.) MYTH: rhIGF-1 is the only form that can be injected in to the muscle to
promote localized growth. Long R3 IGF-1 should be injected into the
bloodsteamin large dosages, between 60 - 100mcg, twice daily.
TRUTH: Long R3 IGF-1 for best results should be injected directly in to
the muscle worked immediately post workout and in smaller dosages,
40 mcg in all bodyparts and 50mcg in quads, divided into each side. For
example, on Bicep day , you would inject 20mcg directly in to each
bicep within 5 minutes post workout. The reason is to cause the IFG-1
to attach to the receptors in the muscle itself. If it is injected in to the
bloodstream in large amounts during the day, it can attach to any IGF
receptors which are located througout the interior membranes of the
body, especially the intestines, the result is you will grow your
intestines. Your intestinal cells will begin to divide and multiply and in a
few months to a year you will have a "perma-gut", and it will keep
growing. Heavy lifting strongly upregulates the IGF-1 receptors on the
stressed muscle, so the muscles you trained are at their beststate for
receiving IGF-1 and growing many new cells. This means PIN
IMMEDIATELY POST WORKOUT and you will get your new muscle cells.
PIN A LESSER AMOUNT and you will only get new muscle cells from your
IGF-1. PIN MORE AND YOU WILL GROW OTHER THINGS SUCH AS A
COLEMAN PERMA-GUT!
FACTS: 40MCG IS plenty! You must realize that this is a huge amount
compared to what the body naturally produces. So 20mcg in each side &
25mcg in the quads: 40-50mcg total, immediately postworkout, in the
muscle worked will let you get plenty of hyperplasia (new cells) without
growing your intestines or other internal organs. Now you won't see major
and immediate mass increases, because that is not what IGF-1 is for.
That's what AAS are for. The newly added muscle cells will take months
to grow, but they will and such a protocol makes using IFG-1 a reasonably
inexpensive protocol. IMPORTANT!!- Research shows that EOD and even
E3rdD IGF-1 treatment is better than ED because ED downregulates the
receptors too quickly. It takes some time for receptors to be able to come
back in full after a megadose of even 20mcg if IGF-1. So you may want to
think about lifting heavy EOD and IFG-1 immediately postworkout every
workout, or 2on/1off and pin the lagging muscle E3D.
FACTS: IGF-1 is synergistic with GH. Most of the effects of GH are
mediated through IGF-1, but not all of them. Among the good effects of
GH that IGF-1 does not exert is anabolism to ligaments. This is just an
example to show that there is benefit to using GH and IGF-1 at the same
time. There is evidence that ED dosing of LR3 reduces GH release in the
body, so it makes plenty of sense to use both at the same time.
SOME CONCLUSIONS:
1.) Immediate Postworkout dosing is all important to creating new cells,
preferably 5 minutes postworkout. One researcher's experience: My
protocol was 5 minutes postworkout in my biceps, delts, and chest
because my research had indicated the postworkout window is very
limited and those were my lagging body parts.
2.) Gains from IGF-1 are difficult to account for. On IGF-1 the gians are
some fat loss, some muscle gain/retention, and many new cells that
will mature and grow in the coming months with lifting and AAS.
3.) Standard Cycle: 40mcg EOD for 4-5 weeks and 4-5 weeks off, and
then repeat the cycle, money permitting. This allow for upgrading of
the receptors. Repeat: EOD or E3D is the optimum protocol.
4.) Injecting posworkout: IGF-1 diluted in AA (Acetic Acid -.5-.6%) is
stable for a year at 98 degrees F, so will keep just fine inside of your
locker at the gym. I wrap my preloaded syringe with an alcohol swab
in a small towel and inject myself in a toilet stall. REMEMBER, IGF-1,
for now, is totally legal, so even if police were brought in they would
only have to apologize politely for the trouble of questioning you,
(in USA)'
I got most of this information from another site, it was much longer, so I
condensed it for you so you could read the highlights. Is all of this true and
accurate? Don't know, but this guy made more sense to me than any other
material I have read. Hope this helps all of you by answering some of your
questions about IGF-1 and Long R3 IGF-1. Fitnessrx
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