MR .T wrote:Ive read plenty of studies that show tamoxifen (nolva) to be better than clomid with less sides. I run nolva for pct without problems unless the cycle is long then I will use HCG at the end of the cycle to kickstart things. You just cant run nolva at 20mg for 4 weeks and call it quits it must be tapered down otherwise the estrogen will shut you dawn again when you stop.
it takes 8 weeks at least to recover with any pct regimen
I recommend nolva pct like this by week 5 you should be basically recovered the rest is just to keep estrogen in check. high estrogen levels will signal receptors in the hypothalamus and shut it down.
week 1-3 40mg
week3-4 30mg
4-5 20mg
5-6 10mg
6-7 5mg
7-8 2.5mg
Check this out bro:
Estrogen receptor blockade with tamoxifen diminishes growth hormone secretion in boys: evidence for a stimulatory role of endogenous estrogens during male adolescence -- Metzger and Kerrigan 79 (2): 513 -- Journal of Clinical Endocrinology & Metaboli Nolva exibited no increase/change in LH or test and even lowered IGF-1 and GH.
Clomid study, notice the dose used just 25mg/day:
Clomiphene Citrate Effects on Testosterone/Estrogen Ratio in Male Hypogonadism
J Sex Med 2005;2:716–721.
ABSTRACT
Aim. Symptomatic late-onset hypogonadism is associated not only with a decline in serum testosterone, but also with a rise in serum estradiol. These endocrine changes negatively affect libido, sexual function, mood, behavior, lean body mass, and bone density. Currently, the most common treatment is exogenous testostosterone therapy. This treatment can be associated with skin irritation, gynecomastia, nipple tenderness, testicular atrophy, and decline in sperm counts. In this study we investigated the efficacy of clomiphene citrate in the treatment of hypogonadism with the objectives of raising endogenous serum testosterone (T) and improving the testosterone/estrogen (T/E) ratio.
Methods. Our cohort consisted of 36 Caucasian men with hypogonadism defined as serum testosterone level less than 300 ng/dL. Each patient was treated with a daily dose of 25 mg clomiphene citrate and followed prospectively. Analysis of baseline and follow-up serum levels of testosterone and estradiol levels were performed.
Results. The mean age was 39 years, and the mean pretreatment testosterone and estrogen levels were 247.6 ± 39.8 ng/dL and 32.3 ± 10.9, respectively. By the first follow-up visit (4–6 weeks), the mean testosterone level rose to 610.0 ± 178.6 ng/dL (P < 0.00001). Moreover, the T/E ratio improved from 8.7 to 14.2 (P < 0.001). There were no side effects reported by the patients.
Conclusions. Low dose clomiphene citrate is effective in elevating serum testosterone levels and improving the testosterone/estadiol ratio in men with hypogonadism. This therapy represents an alternative to testosterone therapy by stimulating the endogenous androgen production pathway.
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